Top 6 Telehealth APIs Enabling Secure and HIPAA-Compliant Virtual Consultations

Telehealth APIs are reshaping healthcare delivery. The global market will reach $3.93 USD billion by 2027, up from $2.53 USD billion in 2021. This demonstrates remarkable growth for a technology that revolutionizes the way patients and providers interact.

The healthcare industry went through a complete transformation after the 2019 Coronavirus pandemic. Telehealth shifted from being optional to becoming essential. Today, 40% of healthcare providers see telehealth API integration as crucial for their business strategies. 

These telemedicine APIs increase efficiency by 40% as they reduce manual work and make data more accessible.

The advantages continue to grow. Healthcare organizations gain needed flexibility since 80% of telehealth API development takes place in the cloud. This explains why 62% of companies point to operational scalability as the main benefit of cloud solutions.

Need the best telehealth solution? iotum leads our recommendations. Their API provides robust security, smooth integration, and complete HIPAA compliance, key features that build patient trust in virtual consultations.

In this piece, we’ll get into the top 6 telehealth APIs that can enhance your healthcare delivery while upholding the highest security and compliance standards.

1. iotum

The iotum telehealth API provides HIPAA-aligned video and voice that embeds into existing clinical systems with minimal development. iotum supports the full visit flow, from booking and reminders to remote consultations and post-visit analytics. 

Access is browser-based, so patients and clinicians can join from any device. Integration options include REST APIs and webhooks for EMR workflows and data capture. The aim is consistent access, fewer missed appointments, and clear insight into visit quality. 

iotum API Key Features

• Scheduling and reminders: Scheduling API with SMS and email notifications, automatic and custom invitations, and click-to-join links that reduce join friction.
• Consultation toolkit: Download-free video and voice, dial-out, text chat, document and screen sharing, waiting rooms, live video annotation, recording, and closed captions, all working across devices.
• Analytics: Visit metrics and post-visit insights to monitor usage and quality

iotum API HIPAA Compliance

The telehealth API is built for healthcare privacy requirements and is presented as HIPAA-compliant. Sessions run over WebRTC, and the product materials emphasize secure communication for protected health information. These safeguards support compliant virtual care across clinics and remote programs.

iotum API Integration Support

The API embeds into EMR and patient portal workflows through REST endpoints and webhooks. Teams can brand the experience, manage notifications, and connect scheduling, messaging, and analytics without replacing existing systems. A published customer example shows the API linking paramedics with physicians to improve time-sensitive care.

Key takeaway:
iotum’s telehealth API brings scheduling, secure video, and analytics together in one integration-ready stack, helping organizations deliver reliable virtual visits across devices while keeping data flows inside current clinical systems.

2. MatrixRTC API

Matrix provides a robust open-source framework that enables telehealth communications through a decentralized architecture and strong security. The telehealth API emphasizes native interoperability while supporting digital sovereignty and privacy.

MatrixRTC API Key Features

Matrix excels by using mandatory end-to-end encrypted communication between devices through the Double Ratchet protocol (also known as “Signal Protocol”). Patient data stays protected even if servers face compromise. 

The system delivers:

• Forward secrecy: Historical data remains safe even if current key data leaks
• Post-compromise security: Future data remains protected despite key leakage
• Cryptographic identity verification: Guards against interception through authentication strings or QR code scanning
• Cryptographic agility: All protocol components can be upgraded under open governance

Matrix continues to strengthen its future-ready capabilities. The system now includes Post Quantum resilience through Kyber post-quantum KEM and PQXDH key exchange.

MatrixRTC API HIPAA Compliance

Healthcare providers must meet HIPAA requirements. Matrix lines up with HIPAA standards by providing:

1. End-to-end encryption using WebRTC Insertable Streams with S-frames encryption frame-by-frame
2. Secure key exchange protocols that prevent network or server interception
3. Protection from TLS man-in-the-middle attacks using pinned certificates
4. Complete data protection during TLS compromise situations

The system avoids unencrypted gateways that could create security risks. This approach helps maintain the high standards needed for HIPAA-compliant telehealth services.

MatrixRTC API Integration Support

Matrix shines in telehealth solution development through its integration features. 

The system includes:

• Enterprise identity management that works with authentication systems like OpenID Connect
• Decentralized communication enabling multiple independent deployments to work together
• Support for cross-domain and cross-classification communication
• Ability to scale to thousands of users per call when using LiveKit as the media server

The system works in full mesh mode for smaller conferences and supports cascaded decentralized conferences across separate instances. This flexibility makes the API suitable for telehealth development in healthcare organizations of all sizes, from small clinics to large hospital networks.

3. Rocket.Chat Calls API

Rocket.Chat offers an open-source platform with secure voice and video calling capabilities for healthcare organizations. Rocket.Chat brings compelling features to organizations that want self-hosted options.

Rocket.Chat Calls API Key Features

Rocket.Chat’s voice calling system runs on WebRTC technology and lets users communicate without switching between apps. 

The platform comes with:

• In-app voice calls: Connect directly within your workspace between users
• Call management: Basic functions like transfer, hold, mute, and unmute
• External calling: Place and receive calls from external phone numbers (with SIP integration)
• Conference calling: Support for multiple video conferencing providers, including Pexip, Jitsi, BigBlueButton, and Google Meet.

HD video and voice capabilities make Rocket.Chat stand out. Healthcare providers can conduct crystal-clear patient consultations. The mobile app’s voice features remain in beta and aren’t available yet.

Rocket.Chat Calls API HIPAA Compliance

Healthcare organizations can rely on Rocket.Chat’s full HIPAA compliance. The platform keeps patient information safe with advanced security features:

• Encryption – Industry-grade encryption for all communications
• Access controls – Role-based permissions limit data access
• Multi-factor authentication – Additional verification layers
• Self-hosted deployment – Complete control over your data environment

HIPAA violations can cost healthcare organizations between $137 and $68,928 per incident. So, Rocket.Chat’s strict compliance standards help organizations protect sensitive patient data.

Rocket.Chat Calls API Integration Support

Rocket.Chat makes telehealth API integration smooth through many connectivity options. Developers can interact with the server programmatically since it’s an open-source platform.

Integration capabilities include:

• Video conferencing connections – Zoom integration supports meeting initiation, scheduling, joining, and recording directly within channels
• External policy APIs – Connect with secure video platforms like Pexip Infinity
• 180+ tools integration – Connect with healthcare applications of all types

Developers working on telehealth solution integration will find Rocket.Chat more flexible than proprietary platforms. Organizations can build telehealth experiences that match their unique workflows and security needs.

4. Quobis API

Quobis leads European unified communications by delivering carrier-class solutions that prioritize security and interoperability for healthcare providers.

Quobis API Key Features

Quobis excels in the eHealth sector through its immediate communication platform. Their technology combines WebRTC and SIP interoperability smoothly. Healthcare organizations can maximize their existing IT investments through this approach. 

Medical facilities benefit by:

• Reducing international calling expenses
• Eliminating toll-free number costs
• Adding communications directly into existing medical applications

Healthcare professionals work with integrated communication tools within their familiar software. This creates optimized workflows with minimal learning curves. Clinical staff can adapt to new telehealth systems quickly.

With over 10 years of groundbreaking WebRTC implementations in more than 30 countries, Quobis stands as a reliable choice for telehealth API development projects that need global reach.

Quobis API HIPAA Compliance

Security and legal compliance are the lifeblood of Quobis’ offering. Their platform keeps patient data secure within your infrastructure instead of routing through third-party servers. Healthcare providers maintain greater control over sensitive information through this architecture.

Quobis stands apart from mainstream alternatives by focusing on network usage and service quality monitoring. This ensures optimal performance during critical patient consultations. Their commitment to privacy protection suits organizations that need strict data handling protocols.

Quobis API Integration Support

Quobis offers a REST-based API that makes shared OSS/BSS integration and configuration tasks possible. This “Service API” (SAPI) works alongside client-side SDKs to help integrate the telehealth API with existing systems.

The platform adjusts its behavior based on customer needs and supports various use cases with the same backend. 

Essential integration features include:

• User and contact management functions
• Presence information retrieval
• Call detail records access
• Authentication platform connections
• Directory integrations

The REST API handles all system administration tasks. Every command runs through the interface. Developers can use CURL or other tools like Postman to work with the API, which simplifies telehealth solution development.

5. TrueConf Server API

TrueConf Server provides a self-hosted 4K telehealth platform that works even without internet. TrueConf has solid features for organizations that need on-premise solutions.

TrueConf Server API Key Features

TrueConf Server API follows RESTful architecture principles and responds to HTTP requests with JSON-formatted data. The API gives healthcare providers many ways to integrate:

• Works offline: Works in private networks without needing the internet
• 4K video support: Makes high-definition telemedicine consultations possible for detailed examinations
• Medical equipment integration: Supports DICOM file sharing and captures video from endoscopes and other devices
• Multi-platform accessibility: Works with popular operating systems and browsers

Healthcare developers like TrueConf’s free version that supports up to 50 participants without time limits. Medical staff can share screens, exchange documents, and monitor patients through encrypted channels.

TrueConf Server API HIPAA Compliance

TrueConf meets the security standards needed for handling protected health information. 

Their HIPAA compliance framework has:

• Private network operations monitored by customers
• Secure connections through SSL/TLS encryption protocols
• Extra protection for video, audio, and content using AES-256 encryption
• Login name and password authentication with administrator control
• Host controls to disconnect participants or end sessions

Healthcare providers should note that TrueConf supports HIPAA security standards. They need to check if TrueConf will sign Business Associate Agreements (BAAs) before handling patient information.

TrueConf Server API Integration Support

The API makes smooth integration with third-party telehealth systems possible through the OAuth 2.0 authorization protocol. 

This approach boosts security by:

1. Letting you control specific permissions based on application needs
2. Using token-based authentication with limited lifespans
3. Supporting both server-wide and user-specific authorization scopes

Telehealth solution developers can use TrueConf’s API to build features like click-to-call widgets on websites for instant video consultations. The complete documentation has examples using cURL and Postman, plus clear guidance to create conferences, manage participants, and build custom telehealth interfaces.

6. Licode API

Licode provides open-source libraries that create secure communication rooms in telehealth applications. Licode takes a different path for developers who build virtual consultation platforms.

Licode API Key Features

Developers get several components from Licode to build telehealth APIs:

• Room Management: Libraries and plug-ins make it easy to create and remove virtual consultation spaces
• Access Control: Token-based authentication system that developers can pass to clients
• Server-Side Components: Backend infrastructure supporting live communication
• Client Libraries: Tools for building browser-based telehealth interfaces

The platform’s security revolves around token-based authentication. Healthcare developers can control access to each virtual consultation room. This system works great for practices that need scheduled appointments with controlled access.

Licode API HIPAA Compliance

Telehealth applications need strict privacy standards, and Licode needs careful setup to meet these requirements. Healthcare providers should take these steps for HIPAA compliance:

1. Configure proper encryption for all patient communications
2. Implement access controls through token authentication
3. Establish a proper BAA (Business Associate Agreement) with hosting providers

Note that HIPAA rules apply to all telehealth services from covered entities. Your telehealth platform must protect patient information according to these standards.

Licode API Integration Support

The token-based access system is central to Licode’s integration approach. Server applications request these tokens and pass them to clients for connection authentication. 

This system offers several benefits:

• Simplified Authentication – No need to pass PHI during authentication
• Granular Access Control – Tokens can be scoped to specific rooms or functions
• Improved Security – Short-lived tokens reduce risk if credentials are compromised

This token system makes development simpler while strengthening security in telehealth API integration projects. Healthcare developers can focus on creating patient-centric experiences instead of managing complex authentication systems.

API Provider	Hosting	Complexity	HIPAA “Out of the Box”
iotum	Cloud/Hybrid	Low	Yes (BAA Available)
MatrixRTC	Decentralized	High	Yes (with E2EE)
Rocket.Chat	Self-Hosted/Cloud	Medium	Yes (HIPAA-ready)
Quobis	Hybrid	Medium	Yes
TrueConf	On-Premises	Medium	High (Local Control)
Licode	Self-Hosted	High	Requires custom setup

Conclusion

Telehealth APIs have revolutionized healthcare delivery since the pandemic. They’ve created new ways to care for patients.

We looked at 6 leading telehealth APIs, and iotum stands out from the pack. Their complete platform delivers top-notch security features and smooth integration options with full HIPAA compliance. 

Healthcare organizations love iotum’s browser-based technology because it doesn’t need downloads. It works on any device while keeping HD audio and video quality.

Security is crucial for any telehealth solution. While all reviewed options provide protection features, iotum’s approach sets the standard. Their end-to-end encryption, strict access controls, and detailed audit logs keep patient information safe during transmission and storage.

Your organization’s specific needs will guide your choice. Large healthcare networks might do better with adaptable options like LiveSwitch or TrueConf Server. Smaller practices often go for ready-to-use solutions like iotum that handle technical details while providing great patient experiences.

Virtual consultations are here to stay in healthcare’s future. Picking the right telehealth API today sets your organization up for tomorrow’s success. 

With its superior security, easy integration, and accessible interface, iotum remains the smart choice for healthcare providers who want to deliver quality virtual care.